
Assay Blocking calprotectin elisa Elisa hama antibodies hmgb1 elisa iron assay Isotype Monoclonal p24 elisa Pcr pge2 elisa plc gamma 2 protein carbonyl assay protein carbonyls Recombinant rna Serum tbars assay kit tdgf1 triglyceride assay Vector
Homozygous missense WIPI2 variants cause a congenital disorder of autophagy with neurodevelopmental impairments of variable clinical severity and disease course
Richard
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WIPI2 is a member of the human WIPI protein household (seven-bladed b-propeller proteins binding phosphatidylinositols, PROPPINs), which play a pivotal position in autophagy and has been implicated within the pathogenesis of a number of neurological situations.
The homozygous WIPI2 variant c.745G>A; p.(Val249Met) (NM_015610.4) has not too long ago been related to a neurodevelopmental dysfunction in a single household. Utilizing exome sequencing and Sanger segregation evaluation, right here, two novel homozygous WIPI2 variants [c.551T>G; p.(Val184Gly) and c.724C>T; p.(Arg242Trp) (NM_015610.4)] had been recognized in 4 people of two consanguineous households.
Moreover, follow-up medical information had been sought from the beforehand reported household. Three non-ambulant affected siblings of the primary household harbouring the p.(Val184Gly) missense variant introduced with microcephaly, profound world developmental delay/mental incapacity, refractory childish/childhood-onset epilepsy, progressive tetraplegia with joint contractures and dyskinesia.
In distinction, the proband of the second household carrying the p.(Arg242Trp) missense variant, just like the initially reported WIPI2 instances, introduced with a milder phenotype, encompassing reasonable mental incapacity, speech and visible impairment, autistic options, and an ataxic gait.
Mind MR imaging in 5 sufferers confirmed distinguished white matter involvement with a world discount in quantity, posterior corpus callosum hypoplasia, irregular dentate nuclei and hypoplasia of the inferior cerebellar vermis. To research the practical influence of those novel WIPI2 variants, we overexpressed each in WIPI2-knockout HEK293A cells.
Compared to wildtype, expression of the Val166Gly WIPI2b mutant resulted in a poor rescue of LC3 lipidation whereas Arg224Trp mutant elevated LC3 lipidation, in keeping with the beforehand reported Val231Met variant. These findings assist a dysregulation of the early steps of the autophagy pathway. Collectively, our findings present proof that biallelic WIPI2 variants trigger a neurodevelopmental dysfunction of variable severity and illness course. Our report expands the medical spectrum and establishes WIPI2-associated dysfunction as a congenital problems of autophagy.
Scientific Efficacy and Security of Human Mesenchymal Stem Cell Remedy for Degenerative Disc Illness: A Systematic Overview and Meta-Evaluation of Randomized Managed Trials
Degenerative disc illness (DDD) may cause extreme low again ache, which can have a severe detrimental influence on the flexibility to carry out each day duties or actions. For the previous few years, mesenchymal stem cell (MSC) transplantation has emerged as a promising technique for the therapy of DDD.
Nevertheless, the medical efficacy of MSC within the therapy of DDD nonetheless lacks medical proof and is controversial. We performed a meta-analysis with randomized managed trials (RCTs) to judge the medical efficacy and security of MSC transplantation in sufferers with DDD. We searched main databases utilizing phrases from the database’s inception by March 2021.
The Cochrane bias danger evaluation device was used to evaluate high quality. The evaluation confirmed that MSC remedy might lower visible analog scale (VAS) scores (SMD = -0.50, 95%CI = -0.68 ~ -0.33, P < 0.00001) and Oswestry Incapacity Index (ODI) scores (SMD = -0.27, 95%CI = -0.44 ~ -0.09, P = 0.003). The outcomes with subgroup evaluation confirmed that MSC remedy might lower VAS scores in Three months (P = 0.001), 6 months (P = 0.01), 12 months (P = 0.02), and ≥24 months (P = 0.002) and ODI scores in ≥24 months (P = 0.006).
Pooled evaluation confirmed that MSC remedy has the next ratio of sufferers at most thresholds however notably on the MIC (minimally vital change) (P = 0.0002) and CSC (clinically vital change) (P = 0.0002) in VAS and MIC (P = 0.0005) and CSC (P = 0.001) ache responders in ODI. Hostile occasions (AE) of treatment-emergent opposed occasions (TEAE), again ache, arthralgia, and muscle spasms weren’t statistically vital between the 2 teams.
Nevertheless, our additional statistical evaluation confirmed that MSC remedy might induce AE of TEAE associated to review therapy (OR = 3.05, 95%CI = 1.11 ~ 8.40, P = 0.03). In conclusion, this examine pooled the primary outcomes and confirmed that MSC remedy might considerably lower VAS and ODI scores in sufferers with DDD. Distinctly, the findings of this meta-analysis counsel a novel therapeutic technique for sufferers with persistent low again ache (LBP) and lumbar dysfunction by DDD.
Complete-Blood Mitochondrial DNA Copies Are Related With the Prognosis of Acute Respiratory Misery Syndrome After Sepsis
Acute respiratory misery syndrome (ARDS) is an inflammatory means of the lungs that develops primarily in response to pulmonary or systemic sepsis, leading to a disproportionate demise toll in intensive care items (ICUs). Given its position as a vital activator of the inflammatory and innate immune responses, earlier research have reported that a rise of circulating cell-free mitochondrial DNA (mtDNA) is a biomarker for deadly end result within the ICU.
Right here we analyzed the affiliation of whole-blood mtDNA (wb-mtDNA) copies with 28-day survival from sepsis and sepsis-associated ARDS. We analyzed mtDNA information from 687 peripheral whole-blood samples inside 24 h of sepsis prognosis from unrelated Spanish sufferers with sepsis (264 with ARDS) included within the GEN-SEP examine.
The wb-mtDNA copies had been obtained from the array intensities of chosen probes, with 100% id with mtDNA and with the biggest variety of mismatches with the nuclear sequences, and normalized throughout the individual-probe intensities. We used Cox regression fashions for testing the affiliation with 28-day survival.
We noticed that wb-mtDNA copies had been considerably related to 28-day survival in ARDS sufferers (hazard ratio = 3.65, 95% confidence interval = 1.39-9.59, p = 0.009) however not in non-ARDS sufferers. Our findings assist that wb-mtDNA copies at sepsis prognosis might be thought of an early prognostic biomarker in sepsis-associated ARDS sufferers. Future research might be wanted to judge the mechanistic hyperlinks of this commentary with the pathogenesis of ARDS.
Identification of Key Candidate Genes and Chemical Perturbagens in Diabetic Kidney Illness Utilizing Built-in Bioinformatics Evaluation
Globally, almost 40 p.c of all diabetic sufferers develop severe diabetic kidney illness (DKD). The identification of the potential early-stage biomarkers and elucidation of their underlying molecular mechanisms in DKD are required. On this examine, we carried out built-in bioinformatics evaluation on the expression profiles GSE111154, GSE30528 and GSE30529 related to early diabetic nephropathy (EDN), glomerular DKD (GDKD) and tubular DKD (TDKD), respectively.
A complete of 1,241, 318 and 280 differentially expressed genes (DEGs) had been recognized for GSE30258, GSE30529, and GSE111154 respectively. Subsequently, 280 upregulated and 27 downregulated DEGs shared between the three GSE datasets had been recognized.
Additional evaluation of the gene expression ranges performed on the hub genes revealed SPARC (Secreted Protein Acidic And Cysteine Wealthy), POSTN (periostin), LUM (Lumican), KNG1 (Kininogen 1), FN1 (Fibronectin 1), VCAN (Versican) and PTPRO (Protein Tyrosine Phosphatase Receptor Kind O) having potential roles in DKD development.
FN1, LUM and VCAN had been recognized as upregulated genes for GDKD whereas the downregulation of PTPRO was related to all three illnesses. Each POSTN and SPARC had been recognized because the overexpressed putative biomarkers whereas KNG1 was discovered as downregulated in TDKD.
Williams-Beuren Syndrome Chromosomal Region 22 Protein (WBSCR22) Antibody |
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abx031474-400ul | Abbexa | 400 ul | EUR 627.6 |
Williams-Beuren Syndrome Chromosomal Region 22 Protein (WBSCR22) Antibody |
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abx031474-80l | Abbexa | 80 µl | EUR 343.2 |
Williams-Beuren Syndrome Chromosomal Region 27 Protein (WBSCR27) Antibody |
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abx025778-400ul | Abbexa | 400 ul | EUR 627.6 |
Williams-Beuren Syndrome Chromosomal Region 27 Protein (WBSCR27) Antibody |
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abx025778-80l | Abbexa | 80 µl | EUR 343.2 |
Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) Antibody |
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20-abx171618 | Abbexa |
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Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) Antibody |
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20-abx129047 | Abbexa |
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Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) Antibody (Biotin) |
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20-abx274484 | Abbexa |
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Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) Polyclonal Antibody (Human) |
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4-PAL307Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) |
Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) Polyclonal Antibody (Human), PE |
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4-PAL307Hu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1). This antibody is labeled with PE. |
Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) Polyclonal Antibody (Human), APC |
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4-PAL307Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1). This antibody is labeled with APC. |
Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) Polyclonal Antibody (Human), Cy3 |
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4-PAL307Hu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1). This antibody is labeled with Cy3. |
Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) Polyclonal Antibody (Human), FITC |
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4-PAL307Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1). This antibody is labeled with FITC. |
Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) Polyclonal Antibody (Human), HRP |
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4-PAL307Hu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1). This antibody is labeled with HRP. |
Recombinant Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) |
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4-RPL307Hu01 | Cloud-Clone |
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Description: Recombinant Human Cat Eye Syndrome Chromosome Region, Candidate 1 expressed in: E.coli |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) Protein |
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20-abx167165 | Abbexa |
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Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) Polyclonal Antibody (Human), APC-Cy7 |
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4-PAL307Hu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1). This antibody is labeled with APC-Cy7. |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) CLIA Kit |
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20-abx190184 | Abbexa |
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Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1)CLIA Kit |
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SCL307Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 6777.36 |
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) in serum, plasma and other biological fluids. |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1)CLIA Kit |
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SCL307Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 663.31 |
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) in serum, plasma and other biological fluids. |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1)CLIA Kit |
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SCL307Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 896.16 |
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) in serum, plasma and other biological fluids. |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1)CLIA Kit |
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SCL307Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3672.72 |
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) in serum, plasma and other biological fluids. |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) CLIA Kit |
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4-SCL307Hu | Cloud-Clone |
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Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1)Serum, plasma and other biological fluids |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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abx055599-96tests | Abbexa | 96 tests | EUR 904.8 |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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abx250398-96tests | Abbexa | 96 tests | EUR 904.8 |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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20-abx151029 | Abbexa |
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Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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DLR-CECR1-Hu-48T | DL Develop | 48T | EUR 664.8 |
Description: A sandwich quantitative ELISA assay kit for detection of Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) in samples from serum, plasma or other biological fluids. |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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DLR-CECR1-Hu-96T | DL Develop | 96T | EUR 870 |
Description: A sandwich quantitative ELISA assay kit for detection of Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) in samples from serum, plasma or other biological fluids. |
Human Cat Eye Syndrome Chromosome Region, Candidate 1(CECR1) ELISA Kit |
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QY-E02201 | Qayee Biotechnology | 96T | EUR 433.2 |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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RDR-CECR1-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 706.8 |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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RDR-CECR1-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 984 |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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RD-CECR1-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 675.6 |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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RD-CECR1-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 939.6 |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 ELISA Kit (CECR1) |
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RK01087 | Abclonal | 96 Tests | EUR 625.2 |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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SEL307Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 6227.58 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) in serum, plasma and other biological fluids. |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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SEL307Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 618.04 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) in serum, plasma and other biological fluids. |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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SEL307Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 831.48 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) in serum, plasma and other biological fluids. |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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SEL307Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3381.66 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) in serum, plasma and other biological fluids. |
Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit |
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4-SEL307Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) in samples from Serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. |
Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) Polyclonal Antibody (Human), Biotinylated |
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4-PAL307Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1). This antibody is labeled with Biotin. |
ELISA kit for Human CECR1 (Cat Eye Syndrome Chromosome Region, Candidate 1) |
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ELK6564 | ELK Biotech | 1 plate of 96 wells | EUR 518.4 |
Description: A sandwich ELISA kit for detection of Cat Eye Syndrome Chromosome Region, Candidate 1 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
ELISA kit for Human CECR1 (Cat Eye Syndrome Chromosome Region, Candidate 1) |
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E-EL-H5495 | Elabscience Biotech | 1 plate of 96 wells | EUR 640.8 |
Description: A sandwich ELISA kit for quantitative measurement of Human CECR1 (Cat Eye Syndrome Chromosome Region, Candidate 1) in samples from Serum, Plasma, Cell supernatant |
CECR1 Cat Eye Syndrome Chromosome Region Candidate 1 Human Recombinant Protein |
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PROTQ9NZK5 | BosterBio | Regular: 10ug | EUR 380.4 |
Description: CECR1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 490 amino acids (30-511a.a.) and having a molecular mass of 56.9kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa).;CECR1 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques. |
CPX Chromosome Region, Candidate 1 (CPXCR1) Antibody |
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abx231948-100ug | Abbexa | 100 ug | EUR 610.8 |
CPX Chromosome Region, Candidate 1 (CPXCR1) Antibody |
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20-abx318624 | Abbexa |
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CPX Chromosome Region, Candidate 1 (CPXCR1) Antibody |
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abx145283-100ug | Abbexa | 100 ug | EUR 469.2 |
CPX Chromosome Region, Candidate 1 (CPXCR1) Antibody |
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20-abx148870 | Abbexa |
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CPX Chromosome Region, Candidate 1 (CPXCR1) Antibody (HRP) |
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20-abx308950 | Abbexa |
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CPX Chromosome Region, Candidate 1 (CPXCR1) Antibody (FITC) |
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20-abx308951 | Abbexa |
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CPX Chromosome Region, Candidate 1 (CPXCR1) Antibody (Biotin) |
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20-abx308952 | Abbexa |
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Chromosome Region Maintenance 1 Protein Homolog (CRM1) Antibody |
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abx231984-100ug | Abbexa | 100 ug | EUR 577.2 |
Amyotrophic Lateral Sclerosis 2 Chromosome Region 12 (ALS2CR12) Antibody |
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20-abx338368 | Abbexa |
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Amyotrophic Lateral Sclerosis 2 Chromosome Region 12 (ALS2CR12) Antibody (HRP) |
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20-abx334692 | Abbexa |
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Amyotrophic Lateral Sclerosis 2 Chromosome Region 12 (ALS2CR12) Antibody (FITC) |
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20-abx334693 | Abbexa |
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Amyotrophic Lateral Sclerosis 2 Chromosome Region 12 (ALS2CR12) Antibody (Biotin) |
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20-abx334694 | Abbexa |
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DSS-AHC Critical Region On The X Chromosome Protein 1 (DAX1) Antibody |
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20-abx142103 | Abbexa |
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DSS-AHC Critical Region On The X Chromosome Protein 1 (DAX1) Antibody |
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abx031637-400ul | Abbexa | 400 ul | EUR 627.6 |
DSS-AHC Critical Region On The X Chromosome Protein 1 (DAX1) Antibody |
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abx031637-80l | Abbexa | 80 µl | EUR 343.2 |
Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 |
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PR27224 | Neuromics | 2 ug | EUR 229.2 |
Human CPX Chromosome Region, Candidate 1 (CPXCR1) ELISA Kit |
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abx384735-96tests | Abbexa | 96 tests | EUR 1093.2 |
Mouse CPX Chromosome Region, Candidate 1 (CPXCR1) ELISA Kit |
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abx388923-96tests | Abbexa | 96 tests | EUR 1093.2 |
Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 Protein |
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20-abx263361 | Abbexa |
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Human Non Imprinted In Prader Willi/Angelman Syndrome Region Protein 1 (NIPA1) ELISA Kit |
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SEJ961Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 5677.8 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Non Imprinted In Prader Willi/Angelman Syndrome Region Protein 1 (NIPA1) in Tissue homogenates, cell lysates and other biological fluids. |
Human Non Imprinted In Prader Willi/Angelman Syndrome Region Protein 1 (NIPA1) ELISA Kit |
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SEJ961Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 572.76 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Non Imprinted In Prader Willi/Angelman Syndrome Region Protein 1 (NIPA1) in Tissue homogenates, cell lysates and other biological fluids. |
Human Non Imprinted In Prader Willi/Angelman Syndrome Region Protein 1 (NIPA1) ELISA Kit |
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SEJ961Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 766.8 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Non Imprinted In Prader Willi/Angelman Syndrome Region Protein 1 (NIPA1) in Tissue homogenates, cell lysates and other biological fluids. |
Human Non Imprinted In Prader Willi/Angelman Syndrome Region Protein 1 (NIPA1) ELISA Kit |
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SEJ961Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3090.6 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Non Imprinted In Prader Willi/Angelman Syndrome Region Protein 1 (NIPA1) in Tissue homogenates, cell lysates and other biological fluids. |
Human Non Imprinted In Prader Willi/Angelman Syndrome Region Protein 1 (NIPA1) ELISA Kit |
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4-SEJ961Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Non Imprinted In Prader Willi/Angelman Syndrome Region Protein 1 (NIPA1) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
DiGeorge Syndrome Critical Region 6 (DGCR6) Antibody |
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abx034439-400ul | Abbexa | 400 ul | EUR 627.6 |
DiGeorge Syndrome Critical Region 6 (DGCR6) Antibody |
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abx034439-80l | Abbexa | 80 µl | EUR 343.2 |
DiGeorge Syndrome Critical Region 14 (DGCR14) Antibody |
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abx027696-400ul | Abbexa | 400 ul | EUR 627.6 |
DiGeorge Syndrome Critical Region 14 (DGCR14) Antibody |
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abx027696-80l | Abbexa | 80 µl | EUR 343.2 |
ELISA kit for Human NIPA1 (Non Imprinted In Prader Willi/Angelman Syndrome Region Protein 1) |
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ELK5358 | ELK Biotech | 1 plate of 96 wells | EUR 518.4 |
Description: A sandwich ELISA kit for detection of Non Imprinted In Prader Willi/Angelman Syndrome Region Protein 1 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Down Syndrome Critical Region Protein 1 (DSCR1) Antibody |
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abx025110-400ul | Abbexa | 400 ul | EUR 627.6 |
Down Syndrome Critical Region Protein 1 (DSCR1) Antibody |
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abx025110-80l | Abbexa | 80 µl | EUR 343.2 |
Down Syndrome Critical Region Protein 1 (DSCR1) Antibody |
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abx025111-400ul | Abbexa | 400 ul | EUR 627.6 |
Down Syndrome Critical Region Protein 1 (DSCR1) Antibody |
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abx025111-80l | Abbexa | 80 µl | EUR 343.2 |
Down Syndrome Critical Region Protein 2 (DSCR2) Antibody |
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abx430430-200ul | Abbexa | 200 ul | EUR 460.8 |
Down Syndrome Critical Region Protein 4 (DSCR4) Antibody |
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20-abx303669 | Abbexa |
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Down Syndrome Critical Region Protein 9 (DSCR9) Antibody |
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20-abx301178 | Abbexa |
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Down Syndrome Critical Region Protein 1 (DSCR1) Antibody |
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20-abx009324 | Abbexa |
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Down Syndrome Critical Region Protein 3 (DSCR3) Antibody |
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abx032797-400ul | Abbexa | 400 ul | EUR 627.6 |
Down Syndrome Critical Region Protein 3 (DSCR3) Antibody |
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abx032797-80l | Abbexa | 80 µl | EUR 343.2 |
DiGeorge Syndrome Critical Region Gene 2 (DGCR2) Antibody |
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abx232350-100ug | Abbexa | 100 ug | EUR 610.8 |
DiGeorge Syndrome Critical Region Gene 8 (DGCR8) Antibody |
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abx232351-100ug | Abbexa | 100 ug | EUR 577.2 |
DiGeorge Syndrome Critical Region Gene 8 (DGCR8) Antibody |
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abx232352-100ug | Abbexa | 100 ug | EUR 661.2 |
DiGeorge Syndrome Critical Region Gene 8 (DGCR8) Antibody |
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abx232353-100ug | Abbexa | 100 ug | EUR 610.8 |
DiGeorge Syndrome Critical Region Gene 8 (DGCR8) Antibody |
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abx037565-100ug | Abbexa | 100 ug | EUR 469.2 |
DiGeorge Syndrome Critical Region Gene 8 (DGCR8) Antibody |
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abx037930-100ug | Abbexa | 100 ug | EUR 469.2 |
DiGeorge Syndrome Critical Region Gene 8 (DGCR8) Antibody |
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20-abx004627 | Abbexa |
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DiGeorge Syndrome Critical Region Gene 8 (DGCR8) Antibody |
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abx430470-200ul | Abbexa | 200 ul | EUR 343.2 |
DiGeorge Syndrome Critical Region Gene 2 (DGCR2) Antibody |
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20-abx112067 | Abbexa |
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DiGeorge Syndrome Critical Region Gene 8 (DGCR8) Antibody |
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20-abx112069 | Abbexa |
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DiGeorge Syndrome Critical Region Gene 8 (DGCR8) Antibody |
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20-abx125324 | Abbexa |
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DiGeorge Syndrome Critical Region Gene 2 (DGCR2) Antibody |
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abx122722-100ug | Abbexa | 100 ug | EUR 469.2 |
DiGeorge Syndrome Critical Region Gene 8 (DGCR8) Antibody |
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abx149799-100ug | Abbexa | 100 ug | EUR 526.8 |
DiGeorge Syndrome Critical Region Gene 8 (DGCR8) Antibody |
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abx034165-400ul | Abbexa | 400 ul | EUR 627.6 |
DiGeorge Syndrome Critical Region Gene 8 (DGCR8) Antibody |
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abx034165-80l | Abbexa | 80 µl | EUR 343.2 |
DiGeorge Syndrome Critical Region Gene 2 (DGCR2) Antibody |
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abx034378-400ul | Abbexa | 400 ul | EUR 627.6 |
DiGeorge Syndrome Critical Region Gene 2 (DGCR2) Antibody |
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abx034378-80l | Abbexa | 80 µl | EUR 343.2 |
Cat Eye Syndrome Critical Region Protein 2 (CECR2) Antibody |
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20-abx136053 | Abbexa |
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Cat Eye Syndrome Critical Region Protein 5 (CECR5) Antibody |
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abx033997-400ul | Abbexa | 400 ul | EUR 627.6 |
Cat Eye Syndrome Critical Region Protein 5 (CECR5) Antibody |
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abx033997-80l | Abbexa | 80 µl | EUR 343.2 |
Cat Eye Syndrome Critical Region Protein 6 (CECR6) Antibody |
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abx029845-400ul | Abbexa | 400 ul | EUR 627.6 |
Cat Eye Syndrome Critical Region Protein 6 (CECR6) Antibody |
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abx029845-80l | Abbexa | 80 µl | EUR 343.2 |
Cat Eye Syndrome Critical Region Protein 2 (CECR2) Antibody |
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abx432490-200ul | Abbexa | 200 ul | EUR 343.2 |
Williams' Medium E |
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CM063-050 | GenDepot | 500ml | EUR 109.2 |
Williams' Medium E |
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CM063-300 | GenDepot | 6x500ml | EUR 319.2 |
Williams' Medium E |
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CM063-310 | GenDepot | 10x500ml | EUR 375.6 |
Williams' Medium E |
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CM063-320 | GenDepot | 20x500ml | EUR 724.8 |
Williams' Medium E |
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CM063-350 | GenDepot | 50x500ml | EUR 1170 |
Putative BPES Syndrome Breakpoint Region Protein (BPESC1) Antibody |
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20-abx311773 | Abbexa |
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Digeorge Syndrome Critical Region Gene 6-Like (DGCR6L) Antibody |
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20-abx112068 | Abbexa |
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ASPSCR1 Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 Human Recombinant Protein |
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PROTQ9BZE9 | BosterBio | Regular: 10ug | EUR 380.4 |
Description: ASPSCR1 Human Recombinant produced in E. coli is a single polypeptide chain containing 576 amino acids (1-553) and having a molecular mass of 62.6kDa. ASPSCR1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
MKS1 Antibody / Meckel syndrome type 1 protein (N-Terminal Region) |
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F54181-0.05ML | NSJ Bioreagents | 0.05 ml | EUR 140.25 |
Description: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. |
MKS1 Antibody / Meckel syndrome type 1 protein (N-Terminal Region) |
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F54181-0.2ML | NSJ Bioreagents | 0.2 ml | EUR 322.15 |
Description: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. |
MKS1 Antibody / Meckel syndrome type 1 protein (N-Terminal Region) |
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F54182-0.05ML | NSJ Bioreagents | 0.05 ml | EUR 140.25 |
Description: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. |
MKS1 Antibody / Meckel syndrome type 1 protein (N-Terminal Region) |
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F54182-0.2ML | NSJ Bioreagents | 0.2 ml | EUR 322.15 |
Description: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. |
DiGeorge Syndrome Critical Region 6-Like Protein (DGCR6L) Antibody |
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20-abx318669 | Abbexa |
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Chromosome 16 Open Reading Frame 14 (MCRIP2) Antibody |
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20-abx111660 | Abbexa |
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Chromosome 16 Open Reading Frame 45 (C16orf45) Antibody |
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abx231034-100ug | Abbexa | 100 ug | EUR 610.8 |
Chromosome 16 Open Reading Frame 70 (C16orf70) Antibody |
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abx231036-100ug | Abbexa | 100 ug | EUR 577.2 |
Chromosome 16 Open Reading Frame 72 (C16orf72) Antibody |
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abx231037-100ug | Abbexa | 100 ug | EUR 610.8 |
Chromosome 16 Open Reading Frame 70 (C16ORF70) Antibody |
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20-abx111661 | Abbexa |
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Chromosome 16 Open Reading Frame 78 (C16ORF78) Antibody |
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20-abx301590 | Abbexa |
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Chromosome 16 Open Reading Frame 62 (C16ORF62) Antibody |
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20-abx302517 | Abbexa |
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Chromosome 16 Open Reading Frame 87 (C16ORF87) Antibody |
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20-abx308129 | Abbexa |
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Anti-Phospho-DiGeorge Syndrome Critical Region 8 DGCR8 (Ser377) Antibody |
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P00475 | BosterBio | 100ul | EUR 477.6 |
Description: Rabbit Polyclonal Phospho-DiGeorge Syndrome Critical Region 8 DGCR8 (Ser377) Antibody. Validated in WB and tested in Human, Mouse. |
Chromosome 16 Open Reading Frame 62 (C16ORF62) Antibody (HRP) |
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20-abx316352 | Abbexa |
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Chromosome 16 Open Reading Frame 87 (C16ORF87) Antibody (HRP) |
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20-abx308130 | Abbexa |
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Chromosome 16 Open Reading Frame 78 (C16ORF78) Antibody (HRP) |
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20-abx309975 | Abbexa |
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Chromosome 16 Open Reading Frame 62 (C16ORF62) Antibody (FITC) |
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20-abx316353 | Abbexa |
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Chromosome 16 Open Reading Frame 87 (C16ORF87) Antibody (FITC) |
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20-abx308131 | Abbexa |
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Chromosome 16 Open Reading Frame 78 (C16ORF78) Antibody (FITC) |
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20-abx309976 | Abbexa |
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DiGeorge Syndrome Critical Region Gene 6 Protein |
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20-abx261930 | Abbexa |
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Chromosome 16 Open Reading Frame 62 (C16ORF62) Antibody (Biotin) |
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20-abx316354 | Abbexa |
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Chromosome 16 Open Reading Frame 87 (C16ORF87) Antibody (Biotin) |
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20-abx308132 | Abbexa |
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Chromosome 16 Open Reading Frame 78 (C16ORF78) Antibody (Biotin) |
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20-abx309977 | Abbexa |
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Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 16 Protein (ALS2CR16) Antibody |
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20-abx148159 | Abbexa |
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DiGeorge Syndrome Critical Region Gene 6-Like Protein |
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20-abx263350 | Abbexa |
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Recombinant (E.Coli) Human Down Syndrome Critical Region 1 |
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RP-785 | Alpha Diagnostics | 5 ug | EUR 196.8 |
RCC1 Antibody / Regulator of Chromosome Condensation |
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RQ5918 | NSJ Bioreagents | 100 ug | EUR 356.15 |
Description: CHC1, also named as RCC1, SNHG3-RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1. The geneID has updated as 1104 recently. |
Rat anti chromosome antibody ELISA kit |
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E02A2057-192T | BlueGene | 192 tests | EUR 1524 |
Description: A sandwich ELISA for quantitative measurement of Rat anti chromosome antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat anti chromosome antibody ELISA kit |
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E02A2057-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A sandwich ELISA for quantitative measurement of Rat anti chromosome antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat anti chromosome antibody ELISA kit |
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E02A2057-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A sandwich ELISA for quantitative measurement of Rat anti chromosome antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog anti chromosome antibody ELISA kit |
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E08A2057-192T | BlueGene | 192 tests | EUR 1524 |
Description: A sandwich ELISA for quantitative measurement of Canine anti chromosome antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Moreover, we additionally recognized two medication, particularly pidorubicine, a topoisomerase inhibitor (LINCS ID- BRD-Okay04548931) and Polo-like kinase inhibitor (LINCS ID- BRD-Okay41652870) having the validated position in reversing the differential gene expression patterns noticed within the three GSE datasets used. Collectively, this examine aids within the understanding of the molecular drivers, vital genes and pathways that underlie DKD initiation and development.
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