Transmembrane serine protease 2 Polymorphisms and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Type 2 Infection: A German Case-Control Study

• Richard

The transmembrane serine protease 2 (TMPRSS2) is the foremost host protease that allows entry of the extreme acute respiratory syndrome coronavirus kind 2 (SARS-CoV-2) into host cells by spike (S) protein priming. Single nucleotide polymorphisms (SNPs) within the gene TMPRSS2 have been related to susceptibility to and severity of H1N1 or H1N9 influenza A virus infections. Purposeful variants could…