
Palmitic acid induces production of proinflammatory cytokines interleukin-6, interleukin-1β, and tumor necrosis factor-α via a NF-κB-dependent mechanism in HaCaT keratinocytes.
Richard
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β-Caryophyllene Mitigates Collagen Antibody Induced Arthritis (CAIA) in Mice By means of a Cross-Discuss between CB2 and PPAR-γ Receptors.
Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke by way of mTOR/Ulk1 pathway.
Novel Hypolipidaemic Medication: Mechanisms Of Motion And Most important Metabolic Results.
Peroxisome Proliferator-Activated Receptor-α Inhibition Protects Towards Doxorubicin-Induced Cardiotoxicity in Mice.
Doxorubicin is an efficient chemotherapeutic drug in opposition to a substantial variety of malignancies. Nevertheless, its poisonous results on myocardium are confirmed as main restrict of utilization. PPAR–α is extremely expressed within the coronary heart, and its activation results in an elevated cardiac fatty acid oxidation and cardiomyocyte necrosis.
This research was carried out to regulate the speculation that PPAR–α receptor inhibition protects in opposition to doxorubicin-induced cardiac dysfunction in mice. Male Balb/c mice have been used on this research. Left atria have been remoted, and their contractility was measured in response to electrical subject stimulation in an ordinary organ bathtub.
PPAR alpha Antibody |
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AF5301 | Affbiotech | 200ul | EUR 420 |
PPAR alpha antibody |
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70R-11927 | Fitzgerald | 100 ug | EUR 632.4 |
Description: Rabbit polyclonal PPAR alpha antibody |
PPAR alpha antibody |
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70R-33651 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit polyclonal PPAR alpha antibody |
PPAR- alpha Antibody |
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ABF5301 | Lifescience Market | 100 ug | EUR 525.6 |
PPAR alpha Antibody / PPARA |
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F54334-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 140.25 |
Description: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. |
PPAR alpha Antibody / PPARA |
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F54334-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 330.65 |
Description: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. |
PPAR alpha Antibody / PPARA |
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RQ7286 | NSJ Bioreagents | 100ug | EUR 419 |
PPAR alpha Polyclonal Antibody |
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30432-100ul | SAB | 100ul | EUR 302.4 |
PPAR alpha Polyclonal Antibody |
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30432-50ul | SAB | 50ul | EUR 224.4 |
Antibody for Human PPAR alpha |
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SPC-1309D | Stressmarq | 0.1ml | EUR 376.8 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is unconjugated. |
Antibody for Human PPAR alpha |
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SPC-1309D-A390 | Stressmarq | 0.1ml | EUR 433.2 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to ATTO 390. |
Antibody for Human PPAR alpha |
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SPC-1309D-A488 | Stressmarq | 0.1ml | EUR 432 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to ATTO 488. |
Antibody for Human PPAR alpha |
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SPC-1309D-A565 | Stressmarq | 0.1ml | EUR 432 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to ATTO 565. |
Antibody for Human PPAR alpha |
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SPC-1309D-A594 | Stressmarq | 0.1ml | EUR 432 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to ATTO 594. |
Antibody for Human PPAR alpha |
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SPC-1309D-A633 | Stressmarq | 0.1ml | EUR 432 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to ATTO 633. |
Antibody for Human PPAR alpha |
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SPC-1309D-A655 | Stressmarq | 0.1ml | EUR 432 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to ATTO 655. |
Antibody for Human PPAR alpha |
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SPC-1309D-A680 | Stressmarq | 0.1ml | EUR 432 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to ATTO 680. |
Antibody for Human PPAR alpha |
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SPC-1309D-A700 | Stressmarq | 0.1ml | EUR 432 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to ATTO 700. |
Antibody for Human PPAR alpha |
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SPC-1309D-ALP | Stressmarq | 0.1ml | EUR 426 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to Alkaline Phosphatase. |
Antibody for Human PPAR alpha |
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SPC-1309D-APC | Stressmarq | 0.1ml | EUR 430.8 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to APC . |
Antibody for Human PPAR alpha |
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SPC-1309D-APCCY7 | Stressmarq | 0.1ml | EUR 518.4 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to APC/Cy7. |
Antibody for Human PPAR alpha |
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SPC-1309D-BI | Stressmarq | 0.1ml | EUR 428.4 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to Biotin. |
Antibody for Human PPAR alpha |
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SPC-1309D-DY350 | Stressmarq | 0.1ml | EUR 523.2 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to Dylight 350. |
Antibody for Human PPAR alpha |
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SPC-1309D-DY405 | Stressmarq | 0.1ml | EUR 494.4 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to Dylight 405. |
Antibody for Human PPAR alpha |
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SPC-1309D-DY488 | Stressmarq | 0.1ml | EUR 471.6 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to Dylight 488. |
Antibody for Human PPAR alpha |
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SPC-1309D-DY594 | Stressmarq | 0.1ml | EUR 476.4 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to Dylight 594. |
Antibody for Human PPAR alpha |
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SPC-1309D-DY633 | Stressmarq | 0.1ml | EUR 464.4 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to Dylight 633. |
Antibody for Human PPAR alpha |
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SPC-1309D-FITC | Stressmarq | 0.1ml | EUR 423.6 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to FITC. |
Antibody for Human PPAR alpha |
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SPC-1309D-HRP | Stressmarq | 0.1ml | EUR 418.8 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to HRP. |
Antibody for Human PPAR alpha |
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SPC-1309D-P594 | Stressmarq | 0.1ml | EUR 440.4 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to PE/ATTO 594. |
Antibody for Human PPAR alpha |
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SPC-1309D-PCP | Stressmarq | 0.1ml | EUR 430.8 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to PerCP. |
Antibody for Human PPAR alpha |
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SPC-1309D-RPE | Stressmarq | 0.1ml | EUR 429.6 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to RPE . |
Antibody for Human PPAR alpha |
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SPC-1309D-STR | Stressmarq | 0.1ml | EUR 430.8 |
Description: A polyclonal antibody for PPAR alpha from Human. The antibody is produced in rabbit after immunization with Human Synthesized unphosphorylated peptide derived from human PPAR ? around the phosphorylation site of serine 21 (L-E-SP-P-L).. The Antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:500), ELISA (1:1000). This PPAR alpha antibody is conjugated to Streptavidin. |
PPAR–α exercise was measured utilizing particular PPAR–α antibody in an ELISA-based system coated with double-strand DNA containing PPAR–α response aspect sequence. Furthermore, cardiac MDA and TNF-α ranges have been measured by ELISA methodology.Following incubation with doxorubicin (35 µM), a big discount in atrial contractility was noticed (P < 0.001). Pretreatment of animals with a selective PPAR–α antagonist, GW6471, considerably improved doxorubicin-induced atrial dysfunction (P < 0.001).